![]() Comparing the COVID-19 vaccines: How are they different? /news/covid-19-vaccine-comparison ![]() Serious blood clots “more likely” with COVID-19 infection than vaccine. ![]() You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. The Johnson and Johnson vaccine only requires one dose, while the Moderna vaccine requires two to be fully effective. This spiked protein then prompts the immune system to produce antibodies to protect against a specific virus. Once the code is in the cells, it produces a spike protein. This kind of vaccine uses a harmless virus to carry a genetic code to the cells. While the Moderna vaccine is an mRNA vaccine, the Johnson & Johnson vaccine is not. How is the Moderna vaccine different from the Johnson & Johnson vaccine? They both also require two doses to be fully effective, although the Pfizer dose is given 21 days after the first, while Moderna is given 28 days after the first dose. They use the same mechanism to build immunity. The Moderna vaccine is similar to the Pfizer vaccine in that both are mRNA vaccines. How is the Moderna vaccine like the Pfizer vaccine? Knowing these can help you make an informed decision and clear up any confusion or misunderstanding. There are similarities and differences among the vaccines. There are several COVID-19 vaccines on the market. How is the Moderna COVID-19 vaccine different from the others?
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